F.A.Q

Frequently Asked Questions



How many hours after the injury can the injection of SportVis™ be made? What is the earliest and latest point of intervention?

The injection is best performed within the first 48 hours because of it is at that point that the maximum of fibrin is present but can be given anytime up to about the 8th day post injury if there are still symptoms.
It can be given soon after the injury once it is properly assessed and stabilised (i.e. within 2 hours of the injury).
SportVis™ can still be injected even if the first 48 hours are missed as SportVis™ might still be able to help the patient recover faster and better even if the recommended injection time frame is missed.

The treatment is explained with 2 injections within 2-3 days time in between. Why this is the optimum number for the treatment? What about doing three injections?

Extremely positive results are seen after 2 injections. Healthcare professionals could inject once more under their own reponsability if they feel clinically the patient need it. The 2-3 days interval before injection number 2 is to give the injury time to rest.

Is it possible to inject directly when the injury happen, for example during a volleyball game?

If the conditions are adequate for an injection, it can be done on the sideline within minutes of the injury. The earliest injection from injury time during the clinical trial of SportVis™was performed about one hour after the sprain.

Is SportVis™ listed on the doping list – that is, can I use it on my elite athletes?

SportVis™ is not listed as a doping agent and can be used on athletes of all standards.

In which way SportVis™ should be injected in case the patient has a haematoma due to the acute ankle sprain?

Injection into a haematoma shoudn’t be performed. A proper assessment of the injury is vital.


Could you specify the place and way of injection?

  • Injury site is first located and assessed.
  • Injection is done with 1 puncture following 3 phases using anatomical landmarks.
  • Locate the area of exquisite tenderness – usually anterior to lateral malleolus (sometimes at distal TFL site)
  • Inject SportVis™ into area of exquisite soreness anterior to CFL using Fanning technique proximally (fibular insertion) to distally (calcaneal insertion) along the lateral malleolus.
  • A third of SportVis™ content is released into the injury site during withdrawal of the syringe during each of the 3 phases. At the end of the injection process, the syringe should be empty.
  • In case of injury to another ligament, another syringe of SportVis™ can be administered in sequence of the first injection if required.
  • More on the Injection technique: see our video on the fanning technique

TFL: Talofibular ligament
CFL: Calcaneo fibular ligament

Why is the fanning technique recommended for SportVis™ injection?

The fanning technique is essential to the administration of SportVis™ as it ensures a physical distribution of SportVis™ which allows larger surface area coverage of the soft tissue for maximum repair.

How does SportVis™ work?

SportVis™’s main ingredient is STABHA™ (Soft Tissue Adapted Biocompatible Hyaluronic Acid).

During the first phase of healing, inflammation at the injury site results in the generation of a fibrin matrix. Due to its high biocompatibility with the soft tissue, SportVis™ interacts with the fibrin matrix.
Moreover SportVis™ has a quieting effect on cells and helps to limit inflammation, optimise recovery and relieve pain at the injury site.
SportVis™ is believed to increase the quality of healing thus reducing scar tissue formation.
SportVis™ is an effective and efficient method of quantitative and qualitative management of ankle sprains as SportVis™ reduces the time to recovery.

Is SportVis™ to replace R.I.C.E. Standard of care?

SportVis™ was not created to replace R.I.C.E.. It is advised that SportVis™ and R.I.C.E. should be used concomitantly.

What is the manufacturing process of SportVis™?

SportVis™ is produced by an innovative manufacturing process which is patented. SportVis™ is derived from continuous fermentation of Streptococcus equi.
After fermentation, the biomass is separated from the solution by filtration to obtain a cell-free solution. This solution is then purified by diafiltration to remove low molecular weight impurities (those derived from the production organism’s metabolism, the residual components of the nutrient medium). The precipitation of nucleic acids and endotoxins is obtained by the addition of a cationic surfactant.
This results in a purity profile that allows SportVis™ to be biocompatible with soft tissues.

What is the molecular weight of SportVis™?

SportVis™ is produced by an innovative manufacturing process which is patented. SportVis™ is derived from continuous fermentation of Streptococcus equi.
After fermentation, the biomass is separated from the solution by filtration to obtain a cell-free solution. This solution is then purified by diafiltration to remove low molecular weight impurities (those derived from the production organism’s metabolism, the residual components of the nutrient medium). The precipitation of nucleic acids and endotoxins is obtained by the addition of a cationic surfactant.
This results in a purity profile that allows SportVis™ to be biocompatiMolecular weight is not the focal point of SportVis™ specific target. SportVis™ design was focused specifically using a very carefully selected set of parameters that gives the optimal rheological properties, thus residence time in the soft tissue.

Purity is also another key factor instead of molecular weight. Both the purity profile and ideal residence time in the soft tissue allows SportVis™ to achieve maximum interactions with the torn ligament.ble with soft tissues.

Can SportVis™ be mixed with other medicine like corticosteroids at injection?

No studies are available on mixing SportVis™ with other medicines therefore this would be dependent on the judgement and responsibility of the Healthcare professional.

Why SportVis™ volume is of 1.2 ml?

This is the studied optimal volume for ankle sprain recovery as this volume has shown to be the most efficient in this case. A larger volume is not used so as not create too much pressure at the injury site.

Where can I find SportVis™?

We have a network of distributors worldwide. Please contact the distributor from your region

PAULHEN CORPORATION