Innovative formulation with High Molecular Weight (HMW) and Low Molecular Weight (LMW) sodium hyaluronates (HA)
Rectal administration with good tolerability
Dual Mode of action
Mode of Action
Facilitates mucosa healing: LMW HA
Provides protective barrier: HMW HA
TRUD is a white enema bottle containing a thick suspension that includes sodium hyaluronate and is used to relieve the symptoms of mild to moderate ulcerative colitis. Ulcerative colitis is a disease of the colon and rectum in which the mucosal lining becomes inflamed. Symptoms include rectal bleeding, frequent diarrhoea and abdominal pain. TRUD™ is applied via the rectum and forms a protective coat over the lining of the distal colon and rectum. This allows the mucosal tissue to heal naturally which reduces the symptoms of ulcerative colitis.
Clinical and endoscopic remission in 50% of patients