Phone: +6221 6387 9525


TRUD Unique Properties

  • Innovative formulation with High Molecular Weight (HMW) and Low Molecular Weight (LMW) sodium hyaluronates (HA)
  • Muco-adhesiveness
  • Rectal administration with good tolerability
  • Dual Mode of action

Mode of Action

  • Facilitates mucosa healing: LMW HA
  • Provides protective barrier: HMW HA

TRUD is a white enema bottle containing a thick suspension that includes sodium hyaluronate and is used to relieve the symptoms of mild to moderate ulcerative colitis. Ulcerative colitis is a disease of the colon and rectum in which the mucosal lining becomes inflamed. Symptoms include rectal bleeding, frequent diarrhoea and abdominal pain. TRUD™ is applied via the rectum and forms a protective coat over the lining of the distal colon and rectum. This allows the mucosal tissue to heal naturally which reduces the symptoms of ulcerative colitis.


  • Symptoms relief
  • Clinical and endoscopic remission in 50% of patients
  • Complete mucosa healing in 25% of patients
  • Optimal safety